Synthesis and antimicrobial study of new tetrazole, benzimidazole and N3-functionalized quinazolinone derivatives

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Synthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities

Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...

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Synthesis of Some New Quinazolinone Derivatives and Evaluation of Their Antimicrobial Activities

Wide range of quinazolinone biological properties including: antibacterial, anticancer, and anti-inflammatory activities encouraged us to synthesis some fused quinazolinone derivatives. Anthranilic acid was condensed with chloro acylchloride followed by dehydration to form the benzoxazinone intermediate; subsequent addition of an amine provided the fused quinazolinones. Deoxyvasicinone which wa...

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ژورنال

عنوان ژورنال: Journal of Scientific Research in Science

سال: 2022

ISSN: ['2356-8364', '2356-8372']

DOI: https://doi.org/10.21608/jsrs.2022.275777